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簡(jiǎn)要描述:Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
產(chǎn)品型號(hào):bsm-52146R
廠(chǎng)商性質(zhì):生產(chǎn)廠(chǎng)家
更新時(shí)間:2025-03-02
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