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簡(jiǎn)要描述:Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.
產(chǎn)品型號(hào):bs-8468R
廠商性質(zhì):生產(chǎn)廠家
更新時(shí)間:2025-02-27
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