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簡(jiǎn)要描述:ZNT8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been foun
產(chǎn)品型號(hào):bs-15382R
廠商性質(zhì):生產(chǎn)廠家
更新時(shí)間:2025-02-27
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